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LeviSelect Immune Cell Depletion Kits
- Untouched enrichment of cell-specific populations
- Simultaneous viable cell enrichment
- Depletion of unwanted contaminants
Uncover the role of immune cells in disease biology
The understanding of the immune system is directly tied to current and future therapeutic approaches regarding human health. The inherent complexity of the immune system, and the critical role it plays in disease pathology, presents scientists with both technical and analytical hurdles that require optimized sample preparation.
Levitation Technology™ on the LeviCell® platform provides a streamlined workflow to obtain untouched immune cells for immunology, oncology, immuno-oncology and drug discovery applications.
Levitate untouched viable cells of interest with LeviSelectTM Depletion Kits
LeviSelectTM Depletion Kits provide a fast and efficient method to deplete a specific cell type away from a mixture of cells or remove several unwanted cell populations. Enrich for untouched viable specific cells of interest (negative selection) while unwanted cells remain in the LeviCell cartridge. The cells of interest remain label-free, ensuring cells are not perturbed.
Observe cell-specific enrichment in
real-time
Experience the enrichment of viable cell-specific cells during the sample processing step like never before. Levitation Technology allows you to confidently proceed with your project knowing that unwanted cell depletion has occurred – see it in real time!
By using fluorescence labeling, though not required, cells can be visualized as they are depleted away from cells of interest during levitation. In this video, see the Calcein AM (green) stained cells move quickly down to the bottom of the separation channel leaving only the CellTracker™ Red stained cells levitating in the top channel.
LeviSelect Immune Cell Enrichment Kits
LeviSelect Immune Kits support cell-specific of the immune subpopulations required for downstream cell analysis or further subsetting. You can enrich hematopoietic populations quickly without lengthy workflows or potential cell activation.
- CD3 Enrichment
- CD4 Enrichment
- CD8 Enrichment
- Pan B Enrichment
- Pan Monocyte Enrichment
- NK Cell Enrichment
The LeviSelect Immune Cell Enrichment Kit portfolio is continually expanding. Inquire to learn about new kits that are available for early access or let us know what cell populations you are interested in isolating.
Flow intensity histogram plots of LeviSelect Human CD45 depletion
LeviSelect CD45 Depletion Kits
For oncology or immuno-oncology research, the LeviSelect CD45 Depletion Kits provide a highly effective method for enriching pure tumor cells enabling characterization for drug discovery and biomarker identification. Human or mouse CD45+ cells are depleted from a mixture of cells in parallel with viable cell enrichment on the LeviCell system. CD45+ cells are retained in the LeviCell cartridge, while CD45- cells of interest remain label-free and are collected for further downstream analysis.
Human Colorectal DTCs - hCD45 depletion
Ordering info
LeviSelect kits
LeviSelect kits can be purchased directly through your local Account Manager.
Depletion Kits
Kit size: 10 rxns/kit
Description:
Depletion of human CD45+ cells from a mixture of cells with simultaneous viable cell enrichment using the LeviCell System. Human CD45+ cells are retained in the LeviCell cartridge, while the human CD45- cells of interest remain label-free and are collected for further downstream analysis.
- Includes Human anti-CD45 Nanospheres, Buffer, and Protocol
- No centrifugation or washing steps required
- Average 20 min run for targeted viable cell enrichment and removal of dead, dying cell or debris
Documents:
Kit size: 10 rxns / kit
Description:
Depletion of mouse CD45+ cells from a mixture of cells with simultaneous viable cell enrichment using the LeviCell System. Mouse CD45+ cells are retained in the LeviCell cartridge, while the mouse CD45- cells of interest remain label-free and are collected for further downstream analysis.
- Includes Mouse anti-CD45 Nanospheres, Buffer, and Protocol
- No centrifugation or washing steps required
- Average 20 min run for targeted viable cell enrichment and removal of dead, dying cell or debris
Documents: