- Applications
3D Cultures
Revolutionize your organoid workflow
Harness magnetic levitation to produce standardized, high-viability organoids and spheroids at scale, reducing formation time from days to hours.
>95%
cell viability
35x
faster formation
5 min
hands-on time
96-well
parallel processing
- The industry problem
Organoid production faces critical bottlenecks
As organoid technologies transition from laboratory proofs-of-concept to clinical and industrial deployment, persistent challenges in reproducibility and scalability have emerged as major barriers.
Reproducibility crisis
Batch-to-batch variability from animal-derived ECMs like Matrigel, with undefined molecular composition and poorly controlled mechanical properties, leads to significant differences in organoid size, morphology and function across experiments and labs.
Kim et al., npj Biomedical Innovations (2026)
Scalability constraints
High-throughput drug screening requires hundreds to tens of thousands of organoids per run. Conventional low-productivity culture methods cannot generate enough uniform organoids per unit area to meet these demands.
Screening platforms require 100s to 10,000s of organoids
Manual, labor-intensive workflows
Conventional organoid culture relies on manual handling: repeated pipetting, media exchange and sample manipulation. That makes it impractical for GMP compliance and blocks the path to standardized, clinical-grade manufacturing.
A barrier to FDA-recognized organoid standards
- Our solution
SALT™ magnetic levitation technology
LevitasBio's Selective Arrayed Levitation Technology uses paramagnetic media and precision magnet arrays to gently separate, enrich and culture cells, without labels, without centrifugation and without compromise.
- Label-free: no antibodies, no beads, no reagent interference
- 96-well parallel: process 96 samples simultaneously for true throughput
- Debris removal: levitation separates viable cells from dead cells and debris
- Results in hours: formation time reduced from 72 hours to 2 hours
- Proven performance
Validated across cell types and organoid models
Consistent results with minimal hands-on time, from input to assay-ready organoids.
Cell yield
Robust recovery regardless of input concentration.
Cell viability
More than 95% viable, even with low-input samples.
Debris removal
Clean inputs from the most compromised samples.
Time to enriched cells
45 minutes per 96-well plate: 5 minutes hands-on, 40 minutes of levitation.
From cells to organoids. Accelerated.
See the difference magnetic levitation makes compared with current methods.
Magnetic levitation enrichment dramatically improves organoid generation efficiency. Top: representative brightfield images of colorectal tumor organoid cultures at Day 0 and Day 5 comparing untreated vs. LeviCell-enriched samples. Enriched samples show visibly higher organoid density and more uniform morphology by Day 5. Scale bars = 200 μm. Bottom: quantitative comparison demonstrating 3.3× improvement in particles per dome (1,040 → 3,388), 3.3× increase in organoid generation efficiency (3% → 10%), and 3.2× higher estimated output (0.9 → 2.9 vials) following LeviCell enrichment. Click the image to enlarge.
- Applications
Enabling the next generation of 3D cell models
From drug screening to assembloid engineering, the LeviCell 96 enables workflows that were previously impractical.
Spheroid & organoid production
Rapid, hands-free production of spheroids with consistent shape, size and density. Magnetic levitation accelerates formation from days to just 2 hours, with built-in viability monitoring.
Real-time drug screening
Monitor cell-to-cell interactions and drug response in real time at single-cell resolution. Density changes reveal viability shifts minutes after compound exposure, with no endpoint assay required.
Multi-layered organoids & assembloids
Build complex, multi-layered organoids by sequentially adding cell types during levitation. Engineer assembloids that recapitulate inter-tissue interactions for advanced disease modeling.
- How it works
Four simple steps
Load
Add cell suspension to LeviCell 96 wells with paramagnetic media.
Levitate
Viable cells rise and cluster at the equilibrium plane in minutes.
Culture
Spheroids form within 2 hours; multi-layered organoids within 2 days.
Collect
Harvest enriched organoids ready for downstream analysis.
- Our solution
LeviCell® 96 System
The only 96-well magnetic levitation platform designed for organoid and spheroid workflows. Process whole or dissociated organoids with unmatched throughput and gentleness.
96
parallel wells
500k
cells per well, maximum
500 µm
maximum sample size
2 h
to spheroid formation
- Organoid data at scale
Built for automated organoid screening
With regulators moving away from animal testing, organoid screens are becoming a primary source of human-relevant data, and the datasets used to train large models of drug response. That only works when thousands of organoids are produced, processed and measured consistently.
The LeviCell® 96 System runs in a standard SLAS/SBS 96-well footprint on the robot deck, so organoid workflows can be scripted end to end instead of pipetted by hand.
Enrich
Remove dead cells and debris from dissociated tumor and organoid inputs.
Wash
Exchange media and buffers without centrifugation.
Image
Integrate imaging to follow formation, response and death in every well.
Collect
Recover whole or dissociated organoids for downstream assays.
Ready to transform your organoid workflow?
See how the LeviCell 96 can accelerate your research, from drug screening to assembloid engineering. Our team will customize a demo for your specific application.