Publications

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Publications

Publications
  • BioRxiv (3)
  • Nature (2)
  • Advanced Materials (1)
  • Haematologica (1)
  • PNAS (1)
  • Research Square (1)
  • Small Materials (1)
  • Wiley Online Library (1)
March 12, 2024
Florian Constanty and colleagues investigate the involvement of border-zone cardiomyocytes and macrophages in the remodeling of the extracellular matrix (ECM) to facilitate cardiomyocyte invasion during cardiac regeneration in zebrafish. The study reveals that these border-zone cardiomyocytes and macrophages actively contribute to modifying the ECM environment, which promotes the invasion of…
Sarah Lindner, PhD, and colleagues investigate the relationship between microbial transformation of bile acids, intestinal immune homeostasis, and inflammatory pathologies. By using a model of graft-versus-host disease (GVHD), the authors were able to determine that T cell-driven inflammation decreased the abundance of microbe-derived metabolites, which are important in reducing T…
February 22, 2024
Jennifer Gansau and colleagues investigate what factors contribute to the degeneration of Intervertebral discs (IVD), a condition that can lead to herniation and back pain due to the poor IVD healing capacities. The authors are able to identify distinct roles of TNFα-receptors (TNFRs) in IVD cell responses, particularly macrophages, to…
Debora Gisch, PhD, and colleagues pioneered a comprehensive epigenomic atlas of the kidney, shedding light on its cellular response to injury and repair. Utilizing the LeviCell® systems for a select number of samples, they purified nuclei from precious kidney biopsy samples and healthy tissue, ensuring high-quality inputs for subsequent single…
Through a high-throughput screen using engineered NALM-16 cells, Holly Pariury, DO, and colleagues discovered that dinaciclib enhances the anti-leukemic effect of venetoclax against hypodiploid Acute Lymphoblastic Leukemia (ALL), an aggressive blood cancer disease with poor prognosis. After lentiviral transduction of the cells, Levitation Technology™ was utilized to improve cell suspension…
Anna Bielecka-Wajdman, PhD, and colleagues investigated proteomic changes in glioblastoma multiforme (GBM) cell lines after Temozolomide (TMZ) treatment. Further, the team used the LeviCell® 1.0 system to efficiently isolate live cells that survived the treatment, enabling the characterization of this TMZ-resistant subpopulation’s morphology and growth by microscopy. The findings provide…