Cell and Gene therapy provides great promise to treat many diseases, such as B-cell malignancies, with FDA-approved CAR-T cells. Immune cells are first isolated from the patient or donor, followed […]

In recent years, single-cell RNA sequencing has transformed our understanding of cellular heterogeneity within highly complex tissues and organs, revealing thus far undiscovered cell types and states and characterizing perturbations […]

Metastases to the central nervous system from solid primary tumors are a frequent and fatal complication of cancer with limited therapeutic options. Despite the advent of immunotherapy, it remains largely […]