Elucidating the Leptomeningeal Immune Response to Cancer With Single-Cell Proteogenomic Profiling
Metastases to the central nervous system from solid primary tumors are a frequent and fatal complication of cancer with limited therapeutic options. Despite the advent of immunotherapy, it remains largely unknown whether and how metastatic cells in the brain and surrounding cerebrospinal fluid (CSF)-filled leptomeninges interact with the immune system. To approach these interactions in […]