Single-Cell Analysis – 3 Pitfalls All Researchers Face
Single-cell analysis has become a key driver of scientific discovery. The move from studying populations of cells to studying single-cells has powered a more detailed and accurate understanding of cellular […]
Give Your Frozen Cells A Vitality Boost
Asking cells to come back to life after cryopreservation is like asking your teenage son or daughter to be out of bed before 10 AM on a Saturday morning. Chances […]
The Power of Visualization
In science, as in many other disciplines, seeing is believing. Fluorescent cell staining is a common and reliable technique to visualize many different aspects of a cell’s state. There are […]
Giving Your Cells a Smoother Ride
Pursuing cell analysis often means trying to give your target cells a ride with the least turbulence: a smooth and steady experience that leaves your cell population calm, relaxed, and […]
Reduce the Garbage in Your scRNA-seq Data
Reduce the Garbage (aka Noise) in Your scRNA-seq Data to Ensure Meaningful Data Single-cell transcriptional data sets can illuminate the path to that rare, elusive cell type lurking in the […]
Basics of Cell Separation Methods: A Deep Dive on Density
Cellular density, defined here as the mass of a cell per unit volume and typically expressed in units of grams per mL or grams per cubic centimeter, is an intrinsic […]
Tumor Dissociation of Highly Viable Cell Suspensions
Tumor Dissociation of Highly Viable Cell Suspensions in Breast Cancer Research Overview – Incidence of Breast Cancer National Breast Cancer Awareness Month started October 1st. This annual spotlight serves as […]
Elevating Organoid Research with Levitation Technology
In 2009, Sato et al. study reported the establishment of the first 3D intestinal organoid culture derived from adult stem cells. Since then, many subsequent organoid protocols for other organs […]
Hepatocyte Isolation and Purification
Hepatocyte Isolation and Purification – A Worldwide Research Priority The largest solid organ in the body is the liver. Made up primarily (i.e., at least 80%) of hepatocytes of various […]
Technical Challenges of Conventional Cell-Sorting Methods
Cell sorting and separation technologies are ubiquitous in molecular biology labs. But their popularity occurred despite serious limitations. Here, we look at some of the major challenges in conventional cell […]